The evidence

100 men. Same treatment. One difference.

Twelve weeks. A hundred men with male-pattern hair loss, all on the same topical at the same dose. One group also had micro-channels opened in the scalp once a week — a route in. The other rubbed it on and hoped.

FIG. 1 — DHURAT 2013, N=100
82%
4.5%
of the micro-channel group reported more than 50% improvement of the topical-only group did

Hair count told the same story: +91.4 hairs vs +22.2 in the measured area.

Same formula. Same dose. The route changed. That was all.

Dhurat 2013

Microneedling in androgenetic alopecia — Int J Trichology, 2013

100 men · 12 weeks · randomized, evaluator-blinded · PMID 23960389

Finding

82% of the microneedling group reported >50% improvement vs 4.5% on topical alone. Mean hair count +91.4 vs +22.2.

Limitation

Both groups used a 5% drug-based topical daily; needling was weekly at 1.5mm — deeper than we build. A pilot study, not a trial of our product.

Read it yourself on PubMed →

Microcirculation After Usage

10 Minutes (After Application)

Before you get excited, read the fine print. We did.

Both groups in that study were using a drug-based topical, and the researchers used a 1.5mm roller — deeper than we build, for reasons you'll see in a second. It is not a trial of our product, and we won't pretend it is. You'd find out in ten minutes anyway.

What the study isolates is one variable, cleanly: hold the formula constant, change only the delivery route, and the outcome moves by an order of magnitude. That result doesn't belong to any ingredient. It belongs to the route.

That explains the route. It doesn't explain us. Two things do.

First: depth is a window, not a dial. Too shallow and the serum dries on the surface like everything you've already tried. Too deep and you're past delivery into injury — inflammation, the one thing a struggling follicle needs less of. When researchers compared depths head-to-head, the shallow needle beat the deep one: 0.6mm produced significantly greater gains in hair count and thickness than the control, while 1.2mm didn't reach significance on either.

That's why our head is fixed at 0.5mm. Not adjustable. Not pressure-dependent. Not “however hard you pressed this morning.” A hand-rolled device can't hold that line, and the line is the product.

Second: an open channel is only worth what you send through it. Which brings us to the formula.

FIG. 2 — FAGHIHI 2021, N=60

Too shallow

Never crosses the barrier. The serum dries on the surface — like every foam before it.

OUR SPEC — 0.5MM

0.5mm — fixed

Through the barrier, then stop. The actives ride the channel down to the follicle.

Too deep

Past delivery, into injury — inflammation a struggling follicle doesn't need.

Faghihi 2021

Comparing two microneedle depths in androgenetic alopecia — J Cosmet Dermatol, 2021

60 men · 12 weeks · 3 arms: topical only / +0.6mm / +1.2mm · PMID 32897622

Finding

The shallow 0.6mm group showed significantly greater gains in hair count (P=0.017) and thickness (P=0.007) vs control. The deeper 1.2mm group didn't reach significance on either.

Limitation

The trial tested 0.6mm; our head is built at 0.5mm. Both needling arms used a drug-based topical alongside.

Read it yourself on PubMed →

Three actives. Three human trials. Three matching doses.

Naming an ingredient with a study behind it is easy — everyone does it. The study only applies if the bottle contains what the trial tested. Ours does, three times over.

The hero

Procyanidin B2

1%

Apple-derived polyphenol, tested double-blind against placebo in men with pattern hair loss. Six months: +6.68 hairs per measured area vs +0.08 on placebo (P<0.005). Terminal hairs — the thick kind that cover scalp — up 1.99 vs a loss of 0.82 on placebo.

trial concentration
Our concentration
Typical competitor — concentration not disclosed

The trial used 1%. So do we.

Kamimura 2000

Topical procyanidin B-2 from apple — Phytomedicine, 2000

29 men · 6 months · double-blind, placebo-controlled · PMID 11194183

Finding

+6.68 hairs per 0.25cm² on 1% procyanidin B-2 vs +0.08 on placebo (P<0.005). Terminal hairs +1.99 vs −0.82 (P<0.02).

Limitation

Small cohort (19 active / 10 placebo). A second supporting trial: Takahashi 2001, PMID 11406858.

Read it yourself on PubMed →

Adenosine

0.75%

Trialled in 102 men over six months: significantly more thick hairs, 80% reporting marked improvement vs 32% on control — replicated in a second, placebo-controlled trial.

trial concentration
Our concentration
Typical competitor — concentration not disclosed

The trials used 0.75%. So do we.

Watanabe 2015

Topical adenosine in Japanese men with AGA — Int J Cosmet Sci, 2015

102 men · 6 months · double-blind, randomized · PMID 25925959

Finding

Significant increase in the proportion of thick hairs; 80% reported at least fairly marked improvement vs 32% on the control lotion.

Limitation

Comparator was a control lotion, not a placebo gel. Replication: Iwabuchi 2016 (38 men, placebo-controlled), PMID 26508659.

Read it yourself on PubMed →

Caffeine

0.2%

210 men, six months, head-to-head against the leading 5% drug topical: non-inferior — 10.59% vs 11.68% anagen improvement, about one point apart, without the drug.

trial concentration
Our concentration
Typical competitor — concentration not disclosed

The trial used 0.2%. So do we.

Dhurat 2017

Caffeine 0.2% vs the leading 5% topical — Skin Pharmacol Physiol, 2017

210 men · 6 months · randomized, multicenter, non-inferiority · PMID 29055953

Finding

Caffeine 0.2% was non-inferior to the 5% drug topical: +10.59% vs +11.68% change in anagen hair ratio.

Limitation

Open-label design — no blinding, no placebo arm. Outcome measured by trichogram anagen ratio, not hair count.

Read it yourself on PubMed →

Go check any competitor's page for these three numbers. The absence is the answer.

The formula the trials describe. The route the trials proved.

Start My Regrowth

$149 for the complete 6-month system — under $25/mo · 120-day money-back guarantee

A dormant follicle didn't die.

It's been producing a finer hair each cycle, and it responds in stages. Judge the system on this schedule, not on week one:

What to expect, and when to judge it

Week 3

Shedding slows

You'll notice it in the drain before you see it in the mirror.

Week 6

The pillow stays clean

The morning check stops turning up strays.

Weeks 8–10

Fine hairs at the temples

You'll blame the bathroom light the first time you see them.

Day 90

The photo tells you

Put it next to your day-one photo. Now you know.

Month 4+

Other people notice

Before you tell them. The 120-day guarantee covers the whole window.

The supporting cast — no inflated claims.

Niacinamide — scalp barrier and comfort between sessions. No growth claim; the research doesn't support one, so we don't make it.

D-Panthenol — measured in fibre testing to raise break stress, so new growth doesn't snap off before it counts.

Sodium hyaluronate, non-crosslinked — small enough to enter the channels and hold the actives there instead of drying on top.

The receipts

Check every number on this page.

Every figure above names its authors, its journal and its PubMed ID — you can hold all of them in your hand in four minutes. We told you the sample sizes, the designs, and the fine print that doesn't flatter us, because a page that shows you half a study isn't evidence. It's decoration.

Now do the same to the rest of your shortlist. Ask what's in it, at what concentration, and which trial used that concentration. Most brands can't answer the second question and won't answer the third.

We just answered first.

120 Days Money-Back Guarantee

You've seen the studies. The last test that matters runs on your own head — and we're paying for it if it fails. Use the system as directed for 120 days. No real change, email us, full refund, keep the product.

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